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hypermethioninemia due to adenosine kinase deficiency
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DOID_0111038 |
[A hypermethioninemia characterized by autosomal recessive inheritance of developmental delay, early-onset seizures, mild dysmorphic features, and characteristic biochemical anomalies, including persistent hypermethioninemia that has_material_basis_in homozygous mutation in the ADK gene on chromosome 10q22.] |
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Coffin-Siris syndrome 5
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DOID_0112368 |
[A Coffin-Siris syndrome characterized by delayed psychomotor development, intellectual disability, coarse facial features, and hypoplasia of the distal phalanges, particularly the fifth digit that has_material_basis_in heterozygous mutation in the SMARCE1 gene on chromosome 17q21.2.] |
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Coffin-Siris syndrome 8
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DOID_0112367 |
[A Coffin-Siris syndrome characterized by variable degrees of impaired intellectual development including speech impairment, hypotonia, feeding difficulties, and behavioral abnormalities and variable occurence of other dysmophic features that has_material_basis_in heterozygous mutation in the SMARCC2 gene on chromosome 12q13.] |
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CADASIL 1
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DOID_0111035 |
[A CADASIL characterized by migraine, strokes, and white matter lesions that has_material_basis_in heterozygous mutation in the NOTCH3 gene on chromosome 19p13.] |
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CADASIL
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DOID_13945 |
[A leukodystrophy characterized by recurrent subcortical ischemic stroke and cognitive impairment.] |
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CADASIL 2
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DOID_0111036 |
[A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26.] |
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dermal bone
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UBERON_0008907 |
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dermal skeletal element
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UBERON_0004756 |
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obsolete lower limb lymph node mast cell malignancy
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DOID_13319 |
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cone-rod dystrophy 16
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DOID_0111022 |
[A cone-rod dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the C8ORF37 gene on chromosome 8q22.] |
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spermatogenic failure 65
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DOID_0112354 |
[A spermatogenic failure characterized by male infertility due to asthenoteratozoospermia with severely reduced or absent progressive sperm motillity and multiple morphologic abnormalities of the flagella that has_material_basis_in homozygous or compound heterozygous mutation in the DHND1 gene on chromosome 11p15.4.] |
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spermatogenic failure 64
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DOID_0112353 |
[A spermatogenic failure characterized by male infertility due to oligoasthenoteratozoospermia or nonobstructive azoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the FBXO43 gene on chromosome 8q22.2.] |
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cone-rod dystrophy 17
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DOID_0111023 |
[A cone-rod dystrophy that has_material_basis_in variation in the chromosome region 10q26.] |
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prostatitis
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DOID_14654 |
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spermatogenic failure 58
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DOID_0112352 |
[A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella and immotile or severely reduced progressive motility of sperm that has_material_basis_in homozygous or compound heterozygous mutation in the IFT74 gene on chromosome 9p21.2.] |
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cone-rod dystrophy 9
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DOID_0111020 |
[A cone-rod dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the ADAM9 gene on chromosome 8p11.] |
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cone-rod dystrophy 15
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DOID_0111021 |
[A cone-rod dystrophy that has_material_basis_in homozygous mutation in the CDHR1 gene on chromosome 10q23.] |
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spermatogenic failure 62
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DOID_0112351 |
[A spermatogenic failure that is characterized by male infertility due to nonobstructive azoospermia with complete metaphase arrest at the spermatocyte stage that has_material_basis_in homozygous or compound heterozygous mutation in the RNF212 gene on chromosome 4p16.3.] |
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spermatogenic failure 61
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DOID_0112350 |
[A spermatogenic failure that is characterized by male infertility due to nonobstructive azoospermia with complete meiotic arrest at the primary spermatocyte stage that has_material_basis_in homozygous or compound heterozygous mutation in the STAG3 gene on chromosome 7q22.1.] |
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toxic optic neuropathy
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DOID_13329 |
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