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Platelet Glycoprotein GPIIb-IIIa Complex
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D019039 |
[Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
] |
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Immunodominant Epitopes
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D23.050.550.500 |
|
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HIV
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B04.820.650.589.650.350 |
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No-Observed-Adverse-Effect Level
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D019055 |
[The daily amount of chemical that can be ingested, which during an entire lifetime appears to be without appreciable health risk. The acceptable daily intake values can be calculated from NO-OBSERVED-ADVERSE-EFFECT LEVEL values.
, The highest dosage administered that does not produce toxic effects.
] |
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Genetic Predisposition to Disease
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D020022 |
[A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
] |
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Adverse Drug Reaction Reporting Systems
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E05.337.800.120 |
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Receptors, Polymeric Immunoglobulin
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D019056 |
[Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
] |
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Quality-Adjusted Life Years
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D019057 |
[A measurement index derived from a modification of standard life-table procedures and designed to take account of the quality as well as the duration of survival. This index can be used in assessing the outcome of health care procedures or services. (BIOETHICS Thesaurus, 1994)
] |
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Community Networks
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D019058 |
[Organizations and individuals cooperating together toward a common goal at the local or grassroots level.
] |
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Rhizotomy
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D019051 |
[Surgical interruption of a spinal or cranial nerve root. (From Dorland, 28th ed)
] |
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Depression, Postpartum
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D019052 |
[Depression in POSTPARTUM WOMEN, usually within four weeks after giving birth (PARTURITION). The degree of depression ranges from mild transient depression to neurotic or psychotic depressive disorders. (From DSM-IV, p386)
] |
|
HIV Enteropathy
|
D019053 |
[A syndrome characterized by chronic, well-established DIARRHEA (greater than one month in duration) without an identified infectious cause after thorough evaluation, in an HIV-positive individual. It is thought to be due to direct or indirect effects of HIV on the enteric mucosa. HIV enteropathy is a diagnosis of exclusion and can be made only after other forms of diarrheal illness have been ruled out. (Harrison's Principles of Internal Medicine, 13th ed, pp1607-8; Haubrich et al., Bockus Gastroenterology, 5th ed, p1155)
] |
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Methacycline
|
D04.615.562.900.525 |
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Evoked Potentials, Motor
|
D019054 |
[The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.
] |
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Adoption
|
I01.880.853.150.140 |
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Acupressure
|
D019050 |
[A type of massage in which finger pressure on specific body sites is used to promote healing, relieve fatigue, etc. Although the anatomical locations are the same as the ACUPUNCTURE POINTS used in ACUPUNCTURE THERAPY (hence acu-), no needle or other acupuncture technique is employed in acupressure. (From Random House Unabridged Dictionary, 2d ed). Shiatsu is a modern outgrowth that focuses more on prevention than healing.
] |
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Base Pairing
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D020029 |
[Pairing of purine and pyrimidine bases by HYDROGEN BONDING in double-stranded DNA or RNA.
] |
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Pyrococcus furiosus
|
D020027 |
[A species of strictly anaerobic, hyperthermophilic archaea which lives in geothermally-heated marine sediments. It exhibits heterotropic growth by fermentation or sulfur respiration.
] |
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Holmium
|
D01.552.550.399.492 |
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Leukotriene Antagonists
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D020024 |
[A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
] |
