|
Crizotinib
|
D000077547 |
[A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.
] |
|
Anaplastic Lymphoma Kinase
|
D000077548 |
[A receptor tyrosine kinase that is essential for development and differentiation of the nervous system in response to secreted growth factors. It phosphorylates the first tyrosine of the Y-x-x-x-Y-Y motif of targets that include PROTO-ONCOGENE PROTEINS C-CBL; INSULIN RECEPTOR SUBSTRATE-1; and MITOGEN-ACTIVATED PROTEIN KINASES, leading to activation of the MAPK signaling pathway and cell proliferation. A chromosomal aberration involving the ALK gene results in its constitutive expression in some cases of NON-HODGKIN LYMPHOMA.
] |
|
Sex Cord-Gonadal Stromal Tumors
|
C04.557.475.750 |
|
|
Neoplasms, Gonadal Tissue
|
C04.557.475 |
|
|
Rural Nursing
|
H02.478.676.806 |
|
|
Sinus Pericranii
|
C16.131.666.190.800 |
|
|
Central Nervous System Vascular Malformations
|
C16.131.666.190 |
|
|
Cebus
|
B01.050.150.900.649.313.988.400.600.150.170.120 |
|
|
Cebinae
|
B01.050.150.900.649.313.988.400.600.150.170 |
|
|
Lymphocyte Activation
|
G12.565 |
|
|
Loneliness
|
F01.470.713 |
|
|
Xylulose
|
D09.947.875.465.920 |
|
|
Ketoses
|
D09.947.875.465 |
|
|
Cornus
|
B01.650.940.800.575.912.250.250.299 |
|
|
Cornaceae
|
B01.650.940.800.575.912.250.250 |
|
|
Atypical Bacterial Forms
|
B05.110 |
|
|
Organism Forms
|
B05 |
|
|
Basiliximab
|
D000077552 |
[A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of the interleukin-2 receptor on the surface of activated T-LYMPHOCYTES. It is used in the prevention of acute graft rejection episodes in patients undergoing renal transplantation.
] |
|
Edaravone
|
D000077553 |
[An antipyrine derivative that functions as a free radical scavenger and neuroprotective agent. It is used in the treatment of AMYOTROPHIC LATERAL SCLEROSIS and STROKE.
] |
|
Ivabradine
|
D000077550 |
[A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.
] |
