|
Spastin
|
D000074181 |
[An AAA ATPase that binds and severs MICROTUBULES. It specifically recognizes and cuts polyglutamylated microtubules with short polyglutamate tails to promote reorganization of cellular microtubule arrays and the release of microtubules from the CENTROSOME following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in AXONS; SPINDLE APPARATUS; and CILIA. Mutations in the spastin gene (SPAST) are associated with type 4 of HEREDITARY SPASTIC PARAPLEGIA.
] |
|
AAA Domain
|
D000074182 |
[Highly conserved amino acid motifs that occur in ATP-binding proteins, especially AAA ATPases. They are characterized by the pattern G-x(4)-GK-[TS]; G, K, T and S are GLYCINE; LYSINE; THREONINE; and SERINE, where x can be any amino acid. This motif binds the beta-phosphate of nucleotides.
, An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
] |
|
ATPases Associated with Diverse Cellular Activities
|
D000074183 |
[A large highly-conserved family of ATPases with diverse functions in cells that are characterized by the presence of a P-LOOP and a ring shape. They couple the energy generated by ATP hydrolysis to remodeling or mechanical translocation of their target molecules.
] |
|
Furin
|
D08.811.277.656.959.350.353 |
|
|
Recruitment, Neurophysiological
|
G07.265.753.760 |
|
|
Receptor Activity-Modifying Protein 2
|
D12.776.543.725.200 |
|
|
Sterol Regulatory Element Binding Proteins
|
D12.776.930.125.500.750 |
|
|
Caspase 9
|
D12.644.360.075.405.550.900 |
|
|
Uterine Cervical Incompetence
|
C13.351.500.852.593.120 |
|
|
Caulobacter crescentus
|
B03.660.050.090.100.100 |
|
|
Caulobacter
|
B03.660.050.090.100 |
|
|
Benzilates
|
D02.241.511.085 |
|
|
Maxillary Fractures
|
C10.900.300.284.500.400.510 |
|
|
Anterior Hypothalamic Nucleus
|
A08.186.211.200.317.357.342.063 |
|
|
Hypothalamus, Anterior
|
A08.186.211.200.317.357.342 |
|
|
Lipopolysaccharide Receptors
|
D12.776.395.550.448.100 |
|
|
Sulfapyridine
|
D02.092.146.807.900 |
|
|
Fibrillin-1
|
D09.400.430.875.500 |
|
|
Azauridine
|
D02.145.451 |
|
|
Physical Distancing
|
N06.850.780.200.688 |
|
