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AVI-4065
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DB05620 |
[AVI-4065, a phosphorodiamidate Morpholino oligomer (PMO), is an investigational antisense HCV drug. It was developed by Sarepta Therapeutics, Inc. After phase II trials it was cancelled due to lack of potency. [L2917]] |
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(3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid
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DB06951 |
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4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
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DB06950 |
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N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)heptadec-3-en-1-yl]acetamide
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DB06960 |
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5-Hydroxy-N-Propargyl-1(R)-Aminoindan
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DB04307 |
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D-4-hydroxyphenylglycine
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DB04308 |
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Asvasiran
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DB05638 |
[Asvasiran is an siRNA that targets the respiratory syncytial virus (RSV) N gene and inhibits viral replication. It has the potential to treat or prevent RSV infection.] |
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2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
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DB06969 |
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1,1'-HEXANE-1,6-DIYLBIS(1H-IMIDAZOLE)
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DB06968 |
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5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine
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DB04306 |
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6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE
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DB06967 |
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4-O-methyl-alpha-D-glucuronic acid
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DB04303 |
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Hexylphosphonic acid (S)-2-methyl-3-phenylpropyl ester
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DB06966 |
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L-Gluconic Acid
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DB04304 |
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Hexylphosphonic acid (R)-2-methyl-3-phenylpropyl ester
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DB06965 |
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Glypromate
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DB05633 |
[Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.] |
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Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone Hydrate
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DB04301 |
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5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE
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DB06964 |
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4-Hydroxy-3,5-Dimethyl-5-(2-Methyl-Buta-1,3-Dienyl)-5h-Thiophen-2-One
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DB04302 |
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3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide
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DB06963 |
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