|
upstream_gene_variant
|
SO_0001631 |
|
|
5KB_downstream_variant
|
SO_0001633 |
|
|
500B_downstream_variant
|
SO_0001634 |
|
|
5KB_upstream_variant
|
SO_0001635 |
|
|
2KB_upstream_variant
|
SO_0001636 |
|
|
susceptibility to bulimia nervosa
|
MIM_607499 |
|
|
Sakati-Nyhan syndrome
|
DOID_0060359 |
[An acrocephalosyndactylia characterized by abnormalities in the bones of the legs, congenital heart defects and craniofacial defects and craniosynostosis. The patients suffer from cyanosis and other respiratory and breathing infections.] |
|
aflatoxin
|
CHEBI_22271 |
[Any of a group of related and highly toxic secondary metabolites (mycotoxins) whose main structural feature is a fused coumarin-bis (dihydrofuran) ring system and which are produced by strains of the moulds Aspergillus flavus or A. parasiticus, together with further metabolites of these mycotoxins.] |
|
multiple acyl-CoA dehydrogenase deficiency
|
DOID_0060358 |
[An inherited metabolic disorder characterized by the body's inability to break down proteins and fats to produce energy. It is a disorder of fatty acid, amino acid, and choline metabolism and has an autosomal recessive inheritance pattern. It has_material_basis_in mutations in the ETFA, ETFB and ETFDH genes. It presents three clinical phenotypes: a neonatal-onset form with congenital anomalies (type I), a neonatal-onset form without congenital anomalies (type II), and a late-onset form (type III). The neonatal-onset forms are usually fatal.] |
|
chylomicron retention disease
|
DOID_0060357 |
[A lipid metabolism disorder characterized by malnutrition, failure to thrive, growth failure, vitamin E deficiency and the absence of chylomicrons and apolipoprotein B48 post-prandially. It has an autosomal recessive inheritance pattern and has_material_basis_in mutations in the SAR1B gene on chromosome 5q31.1.] |
|
Vici syndrome
|
DOID_0060356 |
[A syndrome characterized by callosal agenesis, cataracts, cardiomyopathy, combined immunodeficiency and hypopigmentation. It has_material_basis_in mutation in the EPG5 gene on chromosome 18q12.3.] |
|
amyotrophic lateral sclerosis type 22
|
DOID_0060355 |
[An amyotrophic lateral sclerosis that has_material_basis_in mutation in the TUBA4A gene on chromosome 2q35.] |
|
hemangioma of spleen
|
DOID_256 |
|
|
hemangioma of intra-abdominal structure
|
DOID_254 |
|
|
obsolete abortion complicated by embolism
|
DOID_259 |
|
|
Stormorken syndrome
|
DOID_0060354 |
[A blood platelet disease characterized by thrombocytopathy, thrombocytopenia, mild anemia, asplenia, tubular aggregate myopathy, miosis, headache, and ichthyosis. It has_material_basis_in heterozygous mutation in the STM1 gene on chromosome 11p15. It has an autosomal dominant inheritance pattern.] |
|
acrofacial dysostosis Cincinnati type
|
DOID_0060353 |
[An acrofacial dysostosis characterized by a spectrum of mandibulofacial dysostosis phenotypes, such as cleft palate, micrognathia, malar flattening, microcephaly and, in some cases, extrafacial skeletal defects. It is that has_material_basis_in heterozygous mutation in the POLR1A gene on chromosome 2p11.] |
|
susceptibility to familial breast-ovarian cancer 5
|
MIM_620442 |
|
|
Kleefstra syndrome 1
|
DOID_0060352 |
[A Kleefstra syndrome that is characterized by severe mental retardation, hypotonia, microcephaly, epileptic seizures, flat face with hypertelorism, synophrys, anteverted nares, everted lower lip, carp mouth with macroglossia, and heart defects and that has_material_basis_in a microdeletion in the chromosome region 9q34.3 or by a point mutation in the EHMT1 gene located in that region.] |
|
mitochondrial complex III deficiency nuclear type 2
|
DOID_0060351 |
[A mitochondrial metabolism disease characterized by motor disability, with ataxia, apraxia, dystonia, and dysarthria, associated with necrotic lesions throughout the brain and has_material_basis_in mutation in the TTC19 gene on chromosome 17. It has an autosomal recessive inheritance pattern.] |