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Borjeson-Forssman-Lehmann syndrome
|
DOID_0050681 |
[An X-linked disease that is characterized by intellectual disability, truncal obesity, seizures, hypogonadism, developmental delay, distinctive facial features, tapered fingers and short toes and has_material_basis_in X-linked recessive inheritance of mutations in the PHF6 gene.] |
|
janus kinase-3 deficiency
|
DOID_0060008 |
[A severe combined immunodeficiency that is characterized by severe cell-mediated and antibody-mediated immunodeficiency with recurrent bacterial, viral, and fungal infections, develops_from janus kinase-3 deficiency, and has_material_basis_in autosomal recessive inheritance of mutation in the JAK3 gene of chromosome 19p13.11, responsible for normal differentiation and maturation of B and T immune cells.] |
|
fallopian tube adenosarcoma
|
DOID_1973 |
[A fallopian tube carcinoma that is characterized as a mixture of carcinoma and sarcoma and has_material_basis_in epithelial tissue and has_material_basis_in connective tissue.] |
|
fallopian tube carcinosarcoma
|
DOID_1970 |
[A fallopian tube cancer that is characterized as a mixture of carcinoma and sarcoma and has_material_basis_in epithelial tissue and has_material_basis_in connective tissue.] |
|
Boomerang dysplasia
|
DOID_0050680 |
[An osteochondrodysplasia that is characterized by severe dwarfism, dislocated joints, club feet, distinctive facies and dysplastic tubular bones with boomerang-like bowing, has_material_basis_in heterozygous mutation in the FLNB gene on chromosome 3p14.] |
|
CD3zeta deficiency
|
DOID_0060007 |
[A severe combined immunodeficiency that affects the development and function of T cells.] |
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Bothnia retinal dystrophy
|
DOID_0050683 |
[A fundus dystrophy that is characterized by early onset of night blindness and decreased visual acuity that progresses to blindness in early adulthood, has_material_basis_in mutation in RLBP1 gene.] |
|
obsolete artemis deficiency
|
DOID_0060006 |
[A severe combined immunodeficiency that is caused when the DCLREI1, DNA cross-link repair 1C gene contains mutations resulting in the inability to repair DNA.] |
|
Athabaskan brainstem dysgenesis syndrome
|
DOID_0050682 |
[A brain disease that is characterized by brainstem dysgenesis, has_material_basis_in homozygous mutations in the HOXA1 gene.] |
|
small cell carcinoma
|
DOID_0050685 |
[A carcinoma that is an undifferentiated neoplasm composed of primitive-appearing cells.] |
|
Bowen-Conradi syndrome
|
DOID_0050684 |
[A syndrome that is characterized by growth delays, failure to thrive and malformations of the head and face that results in infantile death, has_material_basis_in homozygous mutation in the EMG1 gene on chromosome 12p13.] |
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inactive_ligand_binding_site
|
SO_0001560 |
|
|
polypeptide_loss_of_function_variant
|
SO_0001559 |
|
|
polypeptide_partial_loss_of_function
|
SO_0001561 |
|
|
polypeptide_post_translational_processing_variant
|
SO_0001562 |
|
|
polypeptide_function_variant
|
SO_0001554 |
|
|
obsolete tuberculous lung cavity
|
DOID_587 |
[A pulmonary tuberculosis characterized by tubercles formation which coalesce into consolidated areas. Caseation and softening of these areas, with involvement of the interstitial tissue, lead to the formation of a cavity. The symptoms include fever, increased cough and sputum.] |
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decreased_translational_product_level
|
SO_0001555 |
|
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increased_translational_product_level
|
SO_0001556 |
|
|
polypeptide_gain_of_function_variant
|
SO_0001557 |
|