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autoimmune thyroiditis
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DOID_7188 |
[An autoimmune disease of endocrine system that involves inflammation located_in thyroid gland caused by the immune system reacting against its own tissues.] |
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combined D-2- and L-2-hydroxyglutaric aciduria
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DOID_0111619 |
[A 2-hydroxyglutaric aciduria characterized by neonatal-onset encephalopathy with severe hypotonia, intractable seizures, respiratory distress, and lack of psychomotor development resulting in early death that has_material_basis_in homozygous or compound heterozygous mutation in the SLC25A1 gene on chromosome 22q11.21.] |
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2-hydroxyglutaric aciduria
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DOID_0050573 |
[An amino acid metabolic disorder that is an autosomal recessive neurometabolic disorder characterized by the significant elevation of urinary levels of hydroxyglutaric acid causing progressive brain damage.] |
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obsolete metastatic childhood sarcoma of soft tissue
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DOID_7186 |
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autosomal recessive spinocerebellar ataxia 6
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DOID_0111617 |
[An autosomal recessive cerebellar ataxia characterized by onset in infancy of nonprogressive cerebellar ataxia without intellectual disability that has_material_basis_in homozygous or compound heterozygous mutation in a region on chromosome 20q11-q13.] |
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autosomal recessive spinocerebellar ataxia 8
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DOID_0111618 |
[An autosomal recessive cerebellar ataxia characterized by slowly progressive neurodegeneration resulting in gait ataxia and other cerebellar signs, spasticity, secondary musculoskeletal abnormalities, and ocular movement anomalies that has_material_basis_in homozygous or compound heterozygous mutation in SYNE1 on chromosome 6q25.2.] |
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autosomal recessive spinocerebellar ataxia 24
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DOID_0111615 |
[An autosomal recessive cerebellar ataxia that has_material_basis_in homozygous or compound heterozygous mutation in the UBA5 gene on chromosome 3q22.1.] |
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autosomal recessive spinocerebellar ataxia 27
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DOID_0111616 |
[An autosomal recessive cerebellar ataxia characterized by adult onset of progressive gait difficulties and other cerebellar signs that has_material_basis_in homozygous or compound heterozygous mutation in the GDAP2 gene on chromosome 1p12.] |
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obsolete Opisthorchis felineus infectious disease
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DOID_0050139 |
[A opisthorchiasis that involves parasitic infection of the liver, biliary ducts, pancreas and pancreatic ducts by Opisthorchis felineus. The symptoms include fever, general malaise, skin rash, gastrointestinal disturbances, severe anemia and liver damage.] |
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podoconiosis
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DOID_0050138 |
[An elephantiasis that is characterized by lymphadema located_in the lower extremities caused by a genetically determined abnormal inflammatory reaction to mineral particles in irritant red clay soils derived from volcanic deposits.] |
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hemophagocytic lymphohistiocytosis
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DOID_0050120 |
[A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a malignancy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages.] |
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obsolete tuberculous encephalitis
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DOID_0050123 |
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distal arthrogryposis type 2B3
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DOID_0111602 |
[A distal arthrogryposis type 2B that has_material_basis_in heterozygous mutation in the MYH3 gene on chromosome 17p13.1.] |
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distal arthrogryposis type 2B
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DOID_0111599 |
[A distal arthrogryposis characterized by contractures of the distal joints of the limbs, triangular face, downslanting palpebral fissures, small mouth, and high arched palate.] |
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distal arthrogryposis type 7
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DOID_0111603 |
[A distal arthrogryposis characterized by inability to open the mouth fully and pseudocamptodactyly that has_material_basis_in heterozygous mutation in the MYH8 gene on chromosome 17p13.1.] |
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distal arthrogryposis type 2B1
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DOID_0111600 |
[A distal arthrogryposis type 2B that has_material_basis_in heterozygous mutation in the TNNI2 gene on chromosome 11p15.5.] |
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distal arthrogryposis type 2B2
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DOID_0111601 |
[A distal arthrogryposis type 2B that has_material_basis_in heterozygous mutation in the TNNT3 gene on chromosome 11p15.5.] |
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maxillary sinus adenoid cystic carcinoma
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DOID_7198 |
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red-green color blindness
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DOID_13909 |
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distal arthrogryposis type 5
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DOID_0111608 |
[A distal arthrogryposis characterized by distal arthrogryposis with ocular abnormalities that has_material_basis_in heterozygous gain of function mutation in the PIEZO2 gene on chromosome 18p11.22-p11.21.] |