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immunodeficiency-centromeric instability-facial anomalies syndrome 3
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DOID_0090010 |
[An immunodeficiency-centromeric instability-facial anomalies syndrome characterized by autosomal recessive inheritance, recurrent infections in childhood and variable dysmorphic facial features that has_material_basis_in homozygous mutation in the CDCA7 gene on chromosome 2q31.] |
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immunodeficiency-centromeric instability-facial anomalies syndrome
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DOID_0090007 |
[A syndrome characterized by immunodeficiency, rearrangements in the vicinity of the centromeres of chromosomes 1, 9, and 16 and facial anomalies in most cases.] |
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eschar
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SYMP_0019158 |
[A skin and integumentary tissue symptom that is characterized by a scab formed especially after a burn.] |
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pancreatic gastrinoma
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DOID_5580 |
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severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive
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DOID_0090013 |
[A severe combined immunodeficiency characterized by being T cell-negative, B cell-negative and natural killer cell-positive and that has_material_basis_in mutation in the RAG1 and RAG2 genes on chromosome 11p12.] |
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severe combined immunodeficiency 104
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DOID_0090014 |
[A severe combined immunodeficiency that is characterized by the onset of recurrent infections in early infancy and that has_material_basis_in homozygous or compound heterozygous mutation in the interleukin-7 receptor gene (IL7R) on chromosome 5p13.] |
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immunodeficiency-centromeric instability-facial anomalies syndrome 4
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DOID_0090011 |
[An immunodeficiency-centromeric instability-facial anomalies syndrome characterized by autosomal recessive inheritance, recurrent infections in childhood and variable dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the HELLS gene on chromosome 10q23.] |
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conjunctivochalasis
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DOID_4250 |
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severe combined immunodeficiency with sensitivity to ionizing radiation
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DOID_0090012 |
[A severe combined immunodeficiency characterized by being T cell-negative, B cell-negative and natural killer cell-positive with sensitivity to ionizing radiation and that has_material_basis_in mutation in the DCLRE1C gene on chromosome 10p13.] |
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melorheostosis
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DOID_4253 |
[An osteosclerosis that has_material_basis_in a mutation of the LEMD3 gene which results_in a hyperdense bony cortex.] |
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epidermolysis bullosa simplex with muscular dystrophy
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DOID_0090017 |
[An syndrome characterized by early childhood onset of progressive muscular dystrophy and blistering skin changes and that has_material_basis_in homozygous or compound heterozygous mutation in the PLEC gene on chromosome 8q24.] |
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lung giant cell carcinoma
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DOID_5583 |
[A lung carcinoma that is located_in large undifferentiated cells.] |
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Alexander disease
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DOID_4252 |
[A leukodystrophy that is characterized by the destruction of white matter and the formation of Rosenthal fibers consisting of abnormal clumps of protein that accumulate in astrocytes.] |
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TNF receptor–associated periodic syndrome
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DOID_0090018 |
[An autoinflammatory disease characterized by recurrent fever, abdominal pain, localized tender skin lesions, arthralgia and myalgia associated with skin, joint, ocular and serosal inflammation that has_material_basis_in heterozygous mutation in the TNFRSF1A gene on chromosome 12p13.] |
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boil
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SYMP_0019160 |
[A skin and integumentary tissue symptom that is characterized by a localized swelling and inflammation of the skin resulting from usually bacterial infection of a hair follicle and adjacent tissue, having a hard central core, and forming pus.] |
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Cenani-Lenz syndactyly syndrome
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DOID_0090015 |
[A dysostosis characterized by syndactyly, malformation of the forearm and lower limb bones, renal hypoplasia or aplasia and that has_material_basis_in homozygous or compound heterozygous mutation in the LRP4 gene on chromosome 11p11.] |
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Ferguson-Smith tumor
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DOID_5585 |
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chromosome 5q deletion syndrome
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DOID_0090016 |
[A chromosomal deletion syndrome characterized by severe macrocytic anemia erythroid hypoplasia in the bone marrow, hypolobated micromegakaryocytes and that has_material_basis_in somatic deletion of 1 allele of the RPS14, MIR145, MIR146A and/or DDX41 genes on chromosome 5q.] |
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muscle tightness
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SYMP_0019162 |
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Caffey disease
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DOID_4257 |
[A bone inflammation disease that causes bone changes, soft tissue swelling and irritability in infants. The disease has been associated with COL1A1 gene. It has symptom soft-tissue swelling, has symptom bone lesions, and has symptom irritability.] |