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Ullrich congenital muscular dystrophy
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DOID_0050558 |
[A congenital muscular dystrophy that is characterized by congenital weakness, hypotonia, proximal joint contractures, marked hyperlaxity of the distal joints, with a loss of ambulation (if achieved) and uniform respiratory insufficiency during childhood that has_material_basis_in mutations in COL6A1, COL6A2 and COL6A3 genes.] |
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autosomal recessive intellectual developmental disorder 82
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DOID_0060947 |
[An autosomal recessive intellectual developmental disorder characterized by global developmental delay with motor and speech delay, variably impaired intellectual development, and behavioral abnormalities has_material_basis_in homozygous mutation in the NSUN6 gene on chromosome 10p12.] |
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hypoventilation
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SYMP_0000428 |
[A respiratory abnormality that is characterized by a deficient ventilation of the lungs that results in reduction in the oxygen content or increase in the carbon dioxide content of the blood or both.] |
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Ullrich congenital muscular dystrophy 2
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DOID_0060948 |
[An Ullrich congenital muscular dystrophy characterized by joint hypermobility, proximal contractures, and muscle weakness precluding ambulation that has_material_basis_in homozygous mutation in the COL12A1 gene on chromosome 6q.] |
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bradypnea
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SYMP_0000429 |
[A respiratory abnormality that is characterized by abnormally slow breathing.] |
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Cryptorchidism
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HP_0000028 |
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Abnormal testis morphology
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HP_0000035 |
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3-hydroxyisobutryl-CoA hydrolase deficiency
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DOID_0060949 |
[An amino acid metabolic disorder characterized by severely delayed psychomotor development, neurodegeneration, increased lactic acid, and brain lesions in the basal ganglia that has_material_basis_in homozygous or compound heterozygous mutation in the HIBCH gene on chromosome 2q32.] |
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macrocytosis
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SYMP_0000426 |
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Abnormal calvaria morphology
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HP_0002683 |
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Abnormal skull morphology
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HP_0000929 |
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sequence_feature
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SO_0000110 |
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claudication
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SYMP_0000424 |
[A pain that is characterized by a leg pain in the calf, or thigh, which is caused by inadequate blood flow to the leg muscles and is brought on by leg exercise such as walking.] |
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reticulocytosis
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SYMP_0000425 |
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intergenic_1kb_variant
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SO_0002074 |
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intergenic_variant
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SO_0001628 |
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transcript_variant
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SO_0001576 |
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incomplete_transcript_3UTR_variant
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SO_0002076 |
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dystonia 33
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DOID_0060940 |
[A dystonia characterized by a neurologic disorder with onset of focal or generalized dystonia in the first decades of life (from early childhood to adolescence) that has_material_basis_in heterozygous mutation in the EIF2AK2 gene on chromosome 2p22.] |
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incomplete_transcript_5UTR_variant
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SO_0002077 |
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