This is just here as a test because I lose it
Term information
definition
A BCRP inhibition assay is a specific in vitro functional assay used to characterize the activity of the Breast Cancer Resistance Protein (BCRP or ABCG2) efflux transporter. It is primarily designed to assess the potential of a test compound (inhibitor) to block BCRP's active transport function, thereby mitigating its efflux activity.
Term relations
Subclass of:
- efflux transporter inhibition assay
- has assay format some cell based format
- has cell line some HEK293
- has detection method some liquid chromatography-tandem mass spectrometry
- has experimental setting only in vitro
- has detection method some scintillation counting
- has cell line some Caco-2 cell
- has endpoint some Ki
- has organism some Homo sapiens
- has substrate only rosuvastatin
- has endpoint some IC50
- has assay design method some liquid chromatography
- has bioassay type some functional
- has organism some Canis lupus familiaris
- has bioassay type some ADME