This is just here as a test because I lose it
Term information
alternative term
bile salt export pump inhibition
inhibition of bile salt export pump
BSEP inhibition
ABCB11 inhibition
definition
A BSEP inhibition assay is a critical in vitro functional assay used to measure the potential of a drug or chemical to inhibit the Bile Salt Export Pump (BSEP), also known as ABCB11. The primary purpose of the assay is to evaluate the risk of Drug-Induced Liver Injury (DILI) associated with a test compound.
Term relations
Subclass of:
- efflux transporter inhibition assay
- has assay format some cell based format
- has experimental setting some in vitro
- has endpoint some IC50
- has cell line some HEK293
- has detection method some scintillation counting
- has bioassay type some functional
- has endpoint some Ki
- has organism some Homo sapiens
- has bioassay type some ADME